Discover the top 25 companies transforming the digital therapeutics market, including NOOM, INC., TELADOC HEALTH, INC., OMADA HEALTH, INC., and other industry leaders. Backed by a market projected to grow from $4.4B to $21.9B by 2028 at a CAGR of 29.1%, this analysis highlights competitive strengths, breakthrough innovations, and strategic moves shaping the future of the industry. Access the full market research report for deeper insights.

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Spotlights on the Industry’s Top Digital Therapeutics Companies

Noom, Inc.

Noom is a leading digital healthcare company founded in 2008 that specializes in behavior change and weight management through its subscription-based mobile application. The company integrates cognitive behavioral therapy (CBT) principles, artificial intelligence, and human coaching to address chronic conditions such as obesity, diabetes, and hypertension. Recently, Noom expanded its offerings with Noom Med, a clinical program providing access to GLP-1 weight-loss medications and specialized medical support, while also targeting the enterprise market through partnerships with major health plans and employers.

Teladoc Health, Inc.

Teladoc Health is a global leader in virtual care and telemedicine, providing a comprehensive suite of services including primary care, mental health, and chronic condition management across more than 175 countries. Through its Livongo and BetterHelp brands, the company offers data-driven digital therapeutics and remote monitoring for diabetes, hypertension, and behavioral health. Teladoc leverages AI and clinical analytics to deliver personalized care at scale, serving a significant portion of Fortune 500 employers and major health systems to improve patient outcomes and reduce healthcare costs.

Omada Health, Inc.

Omada Health is a prominent digital health company focused on chronic disease management through evidence-based behavioral interventions. The company provides virtual care programs for diabetes prevention, type 2 diabetes, hypertension, and musculoskeletal issues, utilizing a combination of connected devices, professional health coaching, and peer support. Omada primarily operates through a business-to-business model, partnering with employers and health plans to improve long-term health habits and clinical markers for their populations.

Welldoc, Inc.

Welldoc is a pioneer in the digital therapeutics space, best known for its BlueStar platform, a digital health solution for individuals living with diabetes. The company focuses on integrating life science and technology to provide clinical-grade, FDA-cleared software that assists in the management of chronic conditions. Welldoc’s platform utilizes data science to deliver personalized real-time feedback and insights to both patients and healthcare providers, aiming to enhance treatment adherence and metabolic control.

CogniFit, Inc.

CogniFit is a digital health company specializing in cognitive assessment and brain training. The company provides a platform of clinically validated digital tasks and games designed to evaluate and improve cognitive functions such as memory, attention, and executive function. CogniFit’s technology is used by individuals, researchers, and healthcare professionals to monitor cognitive health and provide non-pharmacological interventions for various neurological and mental health conditions.

Headspace Health

Headspace Health, formed by the merger of Headspace and Ginger, is a premier provider of digital mental health support and mindfulness-based interventions. The company offers a spectrum of services ranging from guided meditation and sleep tools to on-demand behavioral health coaching and therapy. By integrating consumer-friendly wellness content with clinical mental health services, Headspace Health provides a scalable solution for individuals and organizations seeking to address stress, anxiety, and depression.

Propeller Health

Propeller Health, a subsidiary of ResMed, is a precision digital health company dedicated to improving the management of chronic respiratory diseases like asthma and COPD. The company utilizes FDA-cleared sensors that attach to existing inhalers to track medication usage and identify environmental triggers. Through its mobile application and clinician portal, Propeller provides personalized insights and coaching to improve treatment adherence, reduce emergency visits, and empower patients to better self-manage their conditions.

2Morrow, Inc.

2Morrow is a digital therapeutics provider that delivers evidence-based behavioral change programs via mobile applications. The company’s programs focus on high-impact health issues such as smoking cessation, vaping, weight management, and chronic pain, utilizing Acceptance and Commitment Therapy (ACT) as a core psychological framework. 2Morrow partners with public health organizations, employers, and health plans to offer scalable, private, and effective digital interventions designed to improve long-term wellness outcomes.

Canary Health

Canary Health is a digital therapeutics company that focuses on the self-management of chronic conditions and caregiver support. The company provides a suite of peer-led, evidence-based digital programs designed to help individuals manage diseases such as diabetes, arthritis, and heart disease. Canary Health’s approach emphasizes social support and behavioral science to increase self-efficacy, improve health status, and reduce healthcare utilization for population health stakeholders.

Click Therapeutics, Inc.

Click Therapeutics is a developer of prescription digital therapeutics (PDT) that provides software-based treatments for various medical conditions. The company’s “Clickotine” program for smoking cessation and other pipeline products utilize a proprietary technology platform to deliver personalized behavioral interventions. Click Therapeutics focuses on rigorous clinical validation and partners with major pharmaceutical companies to integrate digital treatments into traditional therapeutic pathways.

Akili, Inc.

Akili is a leading digital therapeutics firm known for developing video game-like cognitive treatments, such as EndeavorRx, which is FDA-cleared for treating ADHD in children. The company’s technology targets specific neural networks in the brain through interactive experiences designed to improve cognitive function. Akili is currently expanding its digital health portfolio through strategic mergers, aiming to provide clinically validated digital treatments for a broader range of neurocognitive and mental health conditions.

Wellthy Therapeutics Pvt. Ltd.

Wellthy Therapeutics is an Asian digital therapeutics company that provides clinically validated, software-based interventions for chronic disease management. The company’s platform focuses on conditions such as diabetes, cardiology, and nephrology, offering real-time coaching and data-driven insights to improve patient outcomes. Wellthy works closely with pharmaceutical companies, insurers, and healthcare providers to augment traditional treatment plans with digital behavioral support.

Cognoa, Inc.

Cognoa is a pediatric behavioral health company specializing in AI-based platforms for the early diagnosis and treatment of behavioral health conditions. Its flagship platform, Canvas Dx, is designed to enable earlier and more equitable diagnosis of autism, allowing for timely intervention. Cognoa is also developing digital solutions for other conditions, such as ADHD and childhood anxiety, with the goal of improving long-term developmental outcomes through early technology-driven care.

Twill Inc.

Twill, formerly known as Happify Health, provides a “The Intelligent Care Wellness Platform” that delivers personalized digital therapeutics and care journeys. The company utilizes evidence-based activities and games rooted in positive psychology and cognitive behavioral therapy to help users manage stress, anxiety, and chronic illness. Twill serves health plans, employers, and pharmaceutical partners by providing a unified digital ecosystem that bridges the gap between wellness and clinical care.

Kaia Health Software GmbH

Kaia Health is a global digital therapeutics company that provides evidence-based treatments for musculoskeletal (MSK) conditions and chronic obstructive pulmonary disease (COPD). The company utilizes advanced computer vision technology via smartphone cameras to provide real-time feedback on physical therapy exercises, ensuring correct form and safety. Kaia Health partners with employers and insurers to provide a scalable, cost-effective alternative to traditional in-person physical therapy and pain management.

Better Therapeutics, Inc.

Better Therapeutics is a prescription digital therapeutics company focused on developing nutritional cognitive behavioral therapy (nCBT) for the treatment of cardiometabolic diseases. Its flagship product, AspyreRx, is the first FDA-authorized CBT app for treating adults with type 2 diabetes. The company’s platform aims to address the behavioral root causes of chronic diseases, providing a scalable digital intervention that can be prescribed by physicians to improve glycemic control and overall health.

Realizedcare

Realizedcare is a digital health provider specializing in comprehensive solutions for chronic pain management and behavioral health. The company offers a platform that integrates digital therapeutics, remote monitoring, and personalized support to help patients navigate the complexities of long-term pain. By focusing on biopsychosocial aspects of health, Realizedcare aims to improve functional outcomes and quality of life for individuals while reducing reliance on high-cost medical interventions.

Biofourmis

Biofourmis is a global technology-enabled care delivery company that uses AI and machine learning to provide personalized remote patient monitoring and digital therapeutics. The company’s platform analyzes physiological data from clinical-grade wearables to predict clinical exacerbations and optimize treatment for conditions such as heart failure and oncology. Biofourmis partners with health systems and pharmaceutical companies to deliver “hospital-at-home” programs and enhance the efficacy of drug therapies through digital augmentation.

Ayogo Incorporated

Ayogo is a behavioral science and health technology company that develops digital platforms designed to improve patient engagement and treatment adherence. The company’s technology utilizes gamification and social psychology to help patients with chronic or complex diseases navigate their care journeys and build healthy habits. Ayogo collaborates with pharmaceutical companies and healthcare providers to create personalized patient support programs that drive better clinical outcomes and health literacy.

Amalgam RX, Inc.

Amalgam Rx is a leading provider of digital medicine and clinical decision support tools. The company’s platform enables the creation and scaling of digital therapeutics and patient support programs across various therapeutic areas, including diabetes and oncology. Amalgam Rx focuses on integrating digital solutions into the clinical workflow, providing data-driven insights to both patients and providers to optimize therapy and improve the management of chronic conditions.

Mindable Health GmbH

Mindable Health is a German-based digital therapeutics company focused on providing evidence-based digital treatments for mental health disorders, specifically panic disorder and agoraphobia. Its flagship app, Mindable, uses cognitive behavioral therapy techniques, including exposure therapy and psychoeducation, to guide users through structured treatment plans. As a certified digital health application (DiGA), it is integrated into the German healthcare system, allowing for physician prescription and insurance reimbursement.

Virta Health Corp.

Virta Health is a technology-enabled healthcare company that focuses on the reversal of type 2 diabetes and other metabolic conditions without medication or surgery. The company utilizes a “treatment-as-a-service” model that combines a specialized ketogenic nutritional protocol with continuous remote monitoring and human coaching. Virta’s approach has demonstrated significant clinical success in reducing A1c levels and eliminating insulin dependence for a high percentage of its members.

Hinge Health

Hinge Health is a leader in the digital musculoskeletal (MSK) clinic space, providing comprehensive virtual care for chronic back and joint pain. The company’s platform combines wearable sensors, personalized exercise therapy, and health coaching to deliver a non-invasive alternative to surgery and opioid use. Hinge Health partners with thousands of employers and health plans to provide a scalable solution that reduces MSK-related healthcare costs and improves employee mobility and productivity.

Orexo AB

Orexo is a specialty pharmaceutical and digital therapeutics company that focuses on treating opioid use disorder and other mental health conditions. Alongside its pharmacological products, Orexo offers a suite of digital therapeutics, such as vorvida for alcohol misuse and deprexis for depression, developed through strategic partnerships. The company aims to provide holistic treatment solutions that combine medication with evidence-based digital behavioral support to improve long-term recovery outcomes.

Freespira, Inc.

Freespira is a digital therapeutics company that provides an FDA-cleared, non-pharmacological treatment for panic attacks, panic disorder, and PTSD symptoms. The company’s intervention focuses on physiological regulation, specifically normalizing respiratory patterns (carbon dioxide levels and breathing rate) through a structured 28-day at-home program. Freespira is used by health plans and providers as a targeted solution to reduce the high cost of emergency care and pharmaceutical reliance associated with anxiety-related conditions.

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